Review Article (Open access) |
---|
SSR Inst. Int. J. Life Sci., 7(5):
2890-2900,
Sep 2021
Prevalence of
Anxiety and Depression in India among Medicos and Non-Medicos during Covid 19: A Survey
Meghna Gupta1, Vitull K Gupta2*,
Navjot Kaur3, Parneet
K Hari4, Kashish Goyal5
1Junior Resident, Department of psychiatry, Maharishi Markandeshwar Medical College and Hospital, Kumarhatti, Solan, Himachal Pradesh, India
2Professor, Department of Medicine, Kishori Ram Hospital and Diabetes Care Centre, Bathinda, Punjab, India
3Associate Professor, Department of Pathology, Government Medical College, Amritsar, Punjab, India
4MBBS Intern, Government Medical College, Patiala, Punjab, India
5MBBS Intern Dayanand Medical College, Ludhiana,
Punjab, India
*Address for Correspondence: Dr. Vitull K Gupta, Professor, Department of
Medicine, Kishori Ram Hospital and Diabetes Care
Centre, Bathinda-151001, Punjab, India
E-mail: vitullgupta2000@yahoo.com
ABSTRACT- Background:
Emerging evidence suggests a significant risk of mental health issues been
associated with disease pandemics in past and during the present COVID-19 pandemic. Generalised
anxiety disorders and depression are considered one of the most common mental
disorders and there is a paucity of studies documenting their prevalence during
the COVID-19 pandemic.
Methods: We conducted this survey using completely voluntary anonymous Generalized Anxiety Disorder Questionnaire-7 (GAD-7) and Patient Health Questionnaire-9 (PHQ-9) by distributing hard copies and e-copies after ethical approval. The anonymous survey questionnaire included socio-demographic characteristics like age, gender, medico or non-medico and residence in Punjab or outside Punjab.
Results: A total of 4333 subjects completed
the survey. The prevalence of anxiety in the study population
was 80.5% including 79.3% among medicos and 81.9% among non-medicos. The
prevalence of depression in the study population was 73.3% including 74.7%
among medicos and 71.7% among non-medicos. Most of the study population,
medicos and non-medicos had mild anxiety and minimal depression as compared to
another level of severity of anxiety and depression.
Conclusion:
Our
survey shows the high prevalence of anxiety and depression as compared to other
studies documented in the literature, necessitating an increased focus on
mental health issues and their psychological impacts to contain and curb grave
adverse effects of anxiety and depression along with the need for early
diagnosis and appropriate management of mental health disorders.
Key Words:
Anxiety, COVID-19, Depression, Minimal depression, Prevalence, SARS-CoV-2
INTRODUCTION- In December 2019 origin of a coronavirus strain called Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2 or COVID-19) was reported at Wuhan in China in a Hunan seafood market [1] and on 20 January 2020, the human-to-human transmission was reported and confirmed.[2] On 30 January 2020, World Health Organisation (WHO) declared COVID-19 as a Public Health Emergency of International Concern and the first case was reported in India. On March 11, 2020, WHO declared the COVID-19 outbreak as a global pandemic [3] and on 23.3.2020 a complete lockdown was enforced by the government of India. Evidence suggests that severe psychological problems have been associated with disease pandemics in past and a systematic review has shown that loneliness and social isolation was associated with worse mental health outcomes.[4] Moreover, the COVID-19 pandemic forcing complete lockdown caused enormous human suffering and adversely affecting the economy causing universal psychosocial impact.[5] Globally, emerging evidence shows that the COVID pandemic presents a significant risk of mental health issues and is recognized as an important mental health care challenge.[6]
The
psychological reaction of the population to any pandemic or disease outbreak
plays an important role in managing the disease pandemic. Despite these facts,
sufficient measures or resources were not provided for attenuating pandemics’ effects on the psychological health
and wellbeing of the population.[7] In pre-COVID-19 times, some
population-based studies and the National Mental Health Survey (2015-16) have
documented the prevalence of anxiety and depression in India.[8] Generalized
Anxiety Disorder Questionnaire-7 (GAD-7) [9] and Patient Health Questionnaire-9 (PHQ-9) [10] are
effective screening tools found to be useful for a diagnosis of GAD and
depression, especially in epidemiological studies and surveys. Preliminary
evidence presented by a review of 28 research articles showed 16-28% symptoms
of anxiety and depression during the COVID-19 pandemic. [11] A systematic review and meta-regression analysis of 29
studies using different assessment scales showed 25.8% (95% CI 20.5–31.9%)
prevalence of anxiety, 24.3% (95% CI 18.2–31.6%) prevalence of depression among
hospital staff engaged in COVID-19 care.[12] There is a paucity of
quantifiable information, which was important for policymakers to make the
appropriate policies to address increasing mental health problems. [13] So we conducted this survey to evaluate the prevalence of
anxiety and depression among the general population including medicos and
non-medicos in India.
MATERIALS AND METHODS
We conducted this survey between 1st October 2020 to 20th February 2021 to assess the prevalence of anxiety and depression in the Indian population during COVID 19 pandemic using hard copies and e-copies of the completely voluntary anonymous questionnaire.
Inclusion criteria- Willingness to participate, Age more than 18 years, Ability to read and understand English.
Exclusion criteria- Not consenting to participate, Age less than 18 years, Unable to read and understand English.
The anonymous survey questionnaire included socio-demographic characteristics like age, gender, medico or non-medico and residence in Punjab or outside Punjab. Anxiety and depression symptoms were assessed by using GAD-7 [9] and PHQ-9 scales.[10] GAD-7 contained seven questions and PHQ-9 contained nine questions to access severity on a 4-point scale of 0–3 ( 0- not at all, 1- several days, 2- more than half the day, 3- nearly every day) rating the symptoms in past two weeks. GAD-7 score of 0-no anxiety, 1-5 mild anxiety, 6-10 moderate anxiety and >11 severe anxiety. [9] PHQ-9 score of 0- no depression, 1–4- minimal depression, 5–9- mild depression, 10–14- moderate depression, 15–19- moderately severe depression and a score of 20–27 indicated severe depression.[10] The GAD-7 and PHQ-9 have been documented as a valid and reliable screening tools used in research studies related to Middle East respiratory syndrome (MERS), Ebola outbreak and covid-19 in China [9,14].
Ethical Approval- Ethical approval was obtained from the Institutional Ethical Committee.
Statistical
Analysis- Data was represented as frequency
and percentage. Association of levels of scores with socio-demographic
variables represented as frequency and percentage was calculated using
Chi-Square Test. P value less than 0.05 was taken as statistically significant
whereas P value more than 0.001 was taken as highly significant. All the
analysis was done using 'IBM SPSS Statistics
for Windows, version 23.0 (IBM Corp., Armonk, N.Y., USA)’.
RESULT
Socio-demographic
characteristics- Table 1 shows the socio-demographic characteristics
of the study population. A total of 4333 subjects participated in the survey,
out of which 2246 (51.8%) were medicos and 2087 (48.2%) were non-medicos. Study
population included 2741(63.3%) males and 1592 (36.7%) females. Medicos group
included 1513 (55.2%) males and 733 (46%) females, whereas non-medicos group
included 1228 (44.8%) males and 859 (54%) females. 2335 (53.9%) study subjects
belonged to Punjab region including 634 (27.2%) medicos and 1701 (72.8%)
non-medicos. 1998 (46.1%) study subjects were from out of Punjab region
including 1612 (80.7%) medicos and 386 (19.3%) non-medicos.
Table 1: Socio-demographic characteristics of the study population, medicos and non-medicos
according to the age groups [N (%)]
Variables |
Study Population |
Medicos |
Non-
Medicos |
||
Total |
4333 |
2246
(51.8) |
2087
(48.2) |
||
Age Group 20-40 years |
Total |
2080 |
972
(46.7) |
1108
(53.3) |
|
Gender |
Male |
1190 |
568
(47.7) |
622
(52.3) |
|
Female |
890 |
404
(45.4) |
486
(54.6) |
||
Region |
Punjab |
1210 |
275
(22.7) |
935
(77.3) |
|
Out
of Punjab |
870 |
697
(80.1) |
173
(19.9) |
||
|
Total |
1854 |
1027
(55.4) |
827
(44.6) |
|
Age Group 41-60 years |
Gender |
Male |
1246 |
748
(60.0) |
498
(40.0) |
Female |
618 |
279
(45.1) |
339
(54.9) |
||
Region |
Punjab |
920 |
292
(31.7) |
628
(68.3) |
|
Out
of Punjab |
854 |
735
(86.1) |
119
(13.9) |
||
Total |
399 |
247
(61.9) |
152
(38.1) |
||
Gender |
Male |
305 |
197
(64.6) |
108
(35.4) |
|
Age Group >60 years |
Female |
94 |
50
(53.2) |
44
(46.8) |
|
Region |
Punjab |
205 |
67
(32.7) |
138
(67.3) |
|
Out
of Punjab |
194 |
180
(92.8) |
14
(7.2) |
Prevalence
of anxiety and depression- Table 2 shows the prevalence of
anxiety (score >1 on GAD-7) in the study population was 80.5% (95% CI
72.50-88.50) and the difference of prevalence of anxiety among
socio-demographic variables was observed to be statistically highly significant
in all sub-groups except region group where it was statistically significant.
The prevalence of depression (score >1 on PHQ-9) in the study
population was 73.3% (95% CI 64.30-82.30) and the difference in the prevalence
of depression among socio-demographic variables was statistically highly
significant except the subgroup of the region where it was statistically
non-significant.
Table 2:
Prevalence of anxiety and depression according to various socio-demographic variables
in study population N (%)
Variables |
No Anxiety |
Anxiety |
x2 value |
P-value |
No Dep. |
Dep. |
x2 value |
P-value |
|
|
Total |
843
(19.5) |
3490 (80.5) |
|
1159 (26.7) |
3174 (73.3) |
|
||
Age |
20-40 Yrs |
409 (19.7) |
1671
(80.2) |
65.81 |
<0.001** |
576
(27.7) |
1504 (72.3) |
16.52 |
<0.001** |
41-60 Yrs |
299 (16.1) |
1555 (83.9) |
449 24.2) |
1405 (75.8) |
|||||
>60 yrs |
135
(33.8) |
264
(66.2) |
134 (33.6) |
265
(66.4) |
|||||
Gender |
Male |
596
(21.7) |
2145 (78.3) |
24.93 |
<0.001** |
830
(30.3) |
1911 (69.7) |
47.52 |
<0.001** |
Female |
247
(15.5) |
1345 (84.5) |
329
(20.7) |
1263 (79.3) |
|||||
Region |
Punjab |
420
(18.0) |
1915 (82.0) |
6.966 |
0.008* |
636
(27.2) |
1699 (72.8) |
0.619 |
0.431;
NS |
Out of Punjab |
423 (21.2) |
1575 (78.8) |
523
(26.2) |
1475 (73.8) |
GAD-7 Scale:
Score 0 No Anxiety, >1 Anxiety. PHQ-9 Scale: Score 0 No Depression (Dep), > 1 Depression (Dep).
P Value: ** Statistically highly significant (p < 0.001), * Statistically significant (p < 0.05),
Statistically
non- significant (p>0.05) (NS)
Table 3: Confidence Interval (CI) for anxiety and depression in the study population and according to variables
|
No Anxiety |
Anxiety |
No Depression |
Depression |
|||||
Variables |
95%
CI |
95%
CI |
95%
CI |
95%
CI |
|||||
|
Lower |
Upper |
Lower |
Upper |
Lower |
Upper |
Lower |
Upper |
|
|
Total |
11.50 |
27.50 |
72.50 |
88.50 |
17.70 |
35.70 |
64.30 |
82.30 |
Age |
20-40 Yrs |
11.70 |
27.70 |
72.30 |
88.30 |
18.70 |
36.70 |
63.30 |
81.30 |
41-60 Yrs |
9.10 |
23.10 |
76.90 |
90.90 |
16.20 |
32.20 |
67.80 |
83.80 |
|
>60 yrs |
24.80 |
42.80 |
57.20 |
75.20 |
24.60 |
42.60 |
57.40 |
75.40 |
|
Gender |
Male |
13.70 |
29.70 |
70.30 |
86.30 |
21.30 |
39.30 |
60.70 |
78.70 |
Female |
8.50 |
22.50 |
77.50 |
91.50 |
12.70 |
28.70 |
71.30 |
87.30 |
|
Region |
Punjab |
10.00 |
26.00 |
74.00 |
90.00 |
18.20 |
36.20 |
63.80 |
81.80 |
Out of Punjab |
13.20 |
29.20 |
70.80 |
86.80 |
17.20 |
35.20 |
64.80 |
82.80 |
GAD-7 Scale: Score 0 No Anxiety, >1
Anxiety. PHQ-9 Scale: Score 0 No Depression, > 1 Depression
Table 4 shows the prevalence of anxiety among medicos was 79.3% and 81.9% among non-medicos and the difference was statistically significant. Prevalence of anxiety between medicos and non-medicos shows the statistically significant difference in sub-groups of 41-60 years age group, > 60 years age group and females whereas in subgroups of 20-40 years age group, males, region both Punjab and outside Punjab, the difference was statistically not-significant. The prevalence of depression among medicos was 74.7% and 71.7% among non-medicos and the difference was statistically significant, whereas the difference was statistically highly significant in sub-groups of 20-40 years age group and males, statistically significant difference in females, those residing in Punjab and the difference was statistically non-significant in 41-60 years age group, > 60 years age group and those residing outside Punjab.
Table 4: Prevalence of anxiety and depression according to
various socio-demographic variables among medicos and non-medicos N (%)
Variables |
Anxiety (Score >1) |
Depression (Score >1) |
|||||||
Medicos |
Non-Medicos |
x2 value |
P value |
Medicos |
Non-Medicos |
x2 value |
P value |
||
|
Total |
1780
(79.3) |
1710
(81.9) |
4.972 |
0.026* |
1677
(74.7) |
1497
(71.7) |
4.760 |
0.029* |
Age |
20-40
Yrs |
790
(81.3) |
881
(79.5) |
1.019 |
0.313;
NS |
744
(76.5) |
760
(68.6) |
16.348 |
<0.001** |
41-60
Yrs |
838
(81.6) |
717
(86.7) |
8.816 |
0.003* |
773
(75.3) |
632
(76.4) |
0.332 |
0.565;
NS |
|
>60
yrs |
152
(61.5) |
112
(73.7) |
6.200 |
0.013* |
160
(64.8) |
105
(69.1) |
0.781 |
0.377;
NS |
|
Gender |
Male |
1182
(78.1) |
963
(78.4) |
0.035 |
0.851;
NS |
1121
(74.1) |
790
(64.3) |
30.578 |
<0.001** |
Female |
598
(81.6) |
747
(87.0) |
8.730 |
0.003* |
556
(75.9) |
707
(82.3) |
10.043 |
0.002* |
|
Region |
Punjab |
513
(80.9) |
1402
(82.4) |
0.711 |
0.399;
NS |
484
(76.3) |
1215
(71.4) |
5.623 |
0.018* |
Out
of Punjab |
1267
(78.6) |
308
(79.8) |
0.266 |
0.606;
NS |
1193
(74.0) |
282
(73.1) |
0.146 |
0.703;
NS |
P Value: **
Statistically highly significant (p < 0.001), * Statistically
significant (p < 0.05), Statistically non-significant (p>0.05) (NS)
Prevalence of anxiety and depression according to severity score: Table 5 shows that 9.5% of subjects had no anxiety, 42.1% mild anxiety, 31.6% moderate and 6.9% subjects had severe anxiety. The comparison among different sub-groups of socio-demographic variables showed a statistically highly significant difference in all sub-groups except the sub-group of the region where it was statistically significant.
Table 5: Prevalence of anxiety (GAD-7 scale) according
to severity among socio-demographic variables in the study population N (%)
Variables |
Study
Population |
x2 value |
P-value |
||||
No anxiety |
Mild anxiety |
Moderate anxiety |
Severe anxiety |
||||
Total |
843
(19.5%) |
1823 (42.1%) |
1369 (31.6%) |
298
(6.9%) |
|
|
|
Age
Groups |
20-40
Yrs |
409
(19.7%) |
897 (43.1%) |
616 (29.6%) |
158
(7.6%) |
90.920 |
<0.001** |
41-60
Yrs |
299 (16.1%) |
800 (43.1%) |
653 (35.2%) |
102 (5.5%) |
|||
>60
yrs |
135 (33.8%) |
126 (31.6%) |
100
(25.1%) |
38 (9.5%) |
|||
Gender |
Male |
596 (21.7%) |
1345
(49.1%) |
662 (24.2%) |
138
(5%) |
274.545 |
<0.001** |
Female |
247 (15.5%) |
478 (30%) |
707 (44.4%) |
160 (10.1%) |
|||
Region |
Punjab |
420 (18%) |
1022 (43.8%) |
735
(31.5%) |
158
(6.8%) |
9.186 |
0.027* |
Out
of Punjab |
423 (21.2%) |
801 (40.1%) |
634
(31.7%) |
140
(7%) |
GAD-7 scale: Score 0: no Anxiety, 1-5 mild anxiety,
6-10 moderate anxiety and >11 severe anxiety
P Value: ** Statistically highly significant (p <
0.001), * Statistically significant (p < 0.05),
Statistically non- significant (p>0.05) (NS)
Table 6 shows the prevalence of anxiety according to severity score in medicos and non-medicos groups and various socio-demographic sub-groups. The difference in severity score of anxiety among medicos and non-medicos was statistically highly significant and in different sub-groups of socio-demographic variables, the difference was statistically highly significant in all sub-groups and statistically not-significant in subgroup of the Punjab region.
Table 6: Prevalence of anxiety according to severity among the
socio-demographic variables and in medicos and non-medicos N (%)
Variables |
Medicos |
Non-Medicos |
x2
value |
P value |
|||||
Mild anxiety |
Moderate anxiety |
Severe anxiety |
Mild anxiety |
Moderate anxiety |
Severe anxiety |
||||
Total |
904 (40.2) |
690 (30.7) |
186 (8.3) |
919 (44.0) |
679 (32.5) |
112 (5.4) |
22.179 |
<0.001** |
|
Age Groups |
20-40 Yrs |
386 (39.7) |
312 (32.1) |
92 (9.5) |
511 (46.1) |
304 (27.4) |
66 (6.0) |
17.937 |
<0.001** |
41-60 Yrs |
426 (41.5) |
340 (33.1) |
72 (7.0) |
374 (45.2) |
313 (37.8) |
30 (3.6) |
21.337 |
<0.001** |
|
>60 yrs |
92 (37.2) |
38 (15.4) |
22 (8.9) |
34 (22.4) |
62 (40.8) |
16 (10.5) |
35.189 |
<0.001** |
|
Gender |
Male |
664 (43.9) |
420 (27.8) |
98 (6.5) |
681 (55.5) |
242 (19.7) |
40 (3.3) |
50.676 |
<0.001** |
Female |
240 (32.7) |
270 (36.8) |
88 (12.0) |
238 (27.7) |
437 (50.9) |
72 (8.4) |
33.434 |
<0.001** |
|
Region |
Punjab |
265 (41.8) |
193 (30.4) |
55 (8.7) |
57 (44.5) |
542 (31.9) |
103 (61) |
6.337 |
0.096(NS) |
Out of Punjab |
639 (39.6) |
497 (30.8) |
131 (8.1) |
162 (42) |
137 (35.5 |
9 (2.3) |
17.689 |
GAD-7
scale: Score 0: no Anxiety, 1-5 mild anxiety, 6-10 moderate anxiety and >11
severe anxiety
P
Value: ** Statistically highly significant (p < 0.001), * Statistically
significant (p < 0.05),
Statistically
non- significant (p>0.05) (NS)
The overall prevalence of depression according to severity score in the study population as well as among various socio-demographic sub-groups is expressed in Table 7. The difference severity score of depression among all the sub-groups of socio-demographic variables was statistically highly significant except in sub-groups of the region where the difference was statistically non-significant.
Table 7: Prevalence of Depression According to Severity among
the Socio-demographic Variables in study population N (%)
|
Study Population |
|
|
|||||
Variables |
Minimal Depression |
Mild Depression |
Moderate
Depression |
Moderately
Severe Dep. |
Severe Depression. |
x2
value |
P value |
|
Total |
1681(38.8%) |
1218 (28.1%) |
229 (5.3%) |
45 (1%) |
1 (0.02%) |
|
|
|
Age Groups |
20-40 Yrs |
767 (36.9%) |
575 (27.6%) |
132 (6.3%) |
30 (1.4%) |
0 (0.0) |
43.095 |
<0.001** |
41-60 Yrs |
786 (42.4%) |
527 (28.4%) |
81 (4.4%) |
10 (0.5%) |
1 (0.1%) |
|||
>60 yrs |
128 (32.1%) |
116 (29.1%) |
16 (4%) |
5 (1.3%) |
0 (0.0) |
|||
Gender |
Male |
1174 42.8%) |
610 (22.3%) |
109 (4%) |
17 (0.6%) |
1 (0.04%) |
194.431 |
<0.001** |
Female |
507 (31.8%) |
608 (38.2%) |
120 (7.5%) |
28 (1.8%) |
0 (0.0) |
|||
Region |
Punjab |
908 (38.9%) |
633 (27.1%) |
132 (5.7%) |
26 (1.1%) |
0 (0.0) |
5.009 |
0.415; NS |
Out of Punjab |
773 (38.7%) |
585 (29.3%) |
97 (4.9%) |
19 (1%) |
1 (0.1%) |
PHQ-9
Scale: Score 0 no Depression, 1-4: Minimal depression, 5-9: Mild depression, 10-14:
Moderate depression, 15-19; Moderately severe depression, 20-27: Sever
depression.
P Value: **Statistically highly
significant (p<0.001), *Statistically significant
(p<0.05), Statistically non- significant (p>0.05) (NS)
The overall prevalence of depression according to severity score in medicos and non-medicos and among various socio-demographic sub-groups is expressed in Table 8. The difference in severity score of depression between medicos and non-medicos was statistically significant. Among different sub-groups of socio-demographic variables, a statistically highly significant difference was observed in subgroups of 20-40 years age, > 60 years of age and males, whereas among females and Punjab region, the difference was statistically significant. Statistically, a non-significant difference was found in sub-groups of 41-60 years of age and out of the Punjab region.
Table 8: Prevalence of depression according to severity among
the socio-demographic variables in medicos and non-medicos N (%)
Variables |
Medicos |
Non-Medicos |
x2
value |
P-value |
|||||||
Minimal Dep |
Mild Dep |
Mod Dep |
Mod severe Dep |
Minimal Dep |
Mild Dep |
Mod Dep |
Mod severe Dep |
||||
Total |
895 (39.8) |
621 (27.6) |
130 (5.8) |
30 (1.3) |
786 (37.7) |
597 (28.6) |
99 (4.7) |
15 (.7) |
12.300 |
0.031* |
|
Age Groups |
20-40 Yrs |
361 (37.1) |
291 (29.9) |
75 (7.7) |
17 (1.7) |
406 (36.6) |
284 (25.6) |
57 (5.1) |
13 (1.2) |
21.915 |
<0.001** |
41-60 Yrs |
434 (42.3) |
283 (27.6) |
47 (4.6) |
8 (0.8) |
352 (42.6) |
244 (29.5) |
34 (4.1) |
2 (.2) |
4.356 |
0.49 (NS) |
|
>60 yrs |
100 (40.5) |
47 (19. 0) |
8 (3.2) |
5 (2.0) |
28 (18.4) |
69 (45.4) |
8 (5.3) |
0 (0) |
41.337 |
<0.001** |
|
Gender |
Male |
658 (43.5) |
375 (24.8) |
75 (5.0) |
12 (.8) |
516 (42.0) |
235 (19.1) |
34 (2.8) |
5 (.4) |
41.981 |
<0.001** |
Female |
237 (32.3) |
246 (33.6) |
55 (7.5) |
18 (2.5) |
270 (31.4) |
362 (42.1) |
65 (7.6) |
10 (1.2) |
19.448 |
0.001* |
|
Region |
Punjab |
274 (43.2) |
154 (24.3) |
45 (7.1) |
11 (1.7) |
634 (37.3) |
479 (28.2) |
87 (5.1) |
15 (9) |
17.073 |
0.002* |
Out of Punjab |
621 (38.5) |
467 (29) |
85 (5.3) |
19 (1.2) |
152 (39.4) |
118 (30.6) |
12 (3.1) |
0 (0) |
8.232 |
0.14(NS) |
PHQ-9 Scale:
Score 0 no Depression, 1-4: Minimal depression (Dep),
5-9: Mild depression (Mild Dep), 10-14: Moderate
depression (Mod Dep), 15-19; Moderately
severe depression (Mod severe Dep), 20-27: Sever
depression.
P Value: ** Statistically highly significant
(p<0.001), *Statistically significant (p<0.05),
Statistically non- significant (p>0.05) (NS)
Response to the question about difficulties to do work, takes care of things at home, or get along with other people show that 57.9 % (2510), 63.7% (1431) and 51.7% (1079) of the total study population, medico and non-medicos respectively did not have any difficulty at all to do work, takes care of things at home, or get along with other people. Whereas somewhat difficulty was felt by 38.3% (1658), 32.4% (728) and 44.6% (930), much difficulty was felt by 3.0% (131), 3.1% (69) and 3.0% (62), extremely difficult was felt by 0.8% (34), 0.8% (18) and 0.8% (16) of total study population, medicos and non-medicos respectively. The difference was observed to be statistically highly significant (x2= 68.724; df= 3; p<0.001).
Response
to the question about the need for treatment among the total study population,
medicos and non-medicos showed that 69.9 % (3030), 66.7% (1497) and
73.5% (1533) of the total study population, medico and non-medicos respectively
did not take any treatment for anxiety or depression. 27.2% (1177), 30.5% (684) and 23.6% (493) of
total study population, medico and non-medicos respectively took occasional treatment,
2.9% (126), 2.9% (65) and 2.9% (61) of total study population, medico and
non-medicos respectively took treatment regularly. The difference between medicos and
non-medicos was observed to be statistically highly significant. (x2= 25.750; df= 2; p < 0.001).
DISCUSSION- Historically, any disease pandemics are associated with
serious psychological and mental health consequences. Evidence suggests mental
health issues like stress, depression, anxiety, sleep disturbances, fear, anger
and denial has escalated during the Covid-19 pandemic globally among general
and vulnerable populations.[15] Assessment of mental health
issues is important for planning strategies to prevent and manage mental health
issues.
We conducted this survey to document the prevalence of
anxiety and depression using GAD-7 and PHQ-9 scales respectively and found prevalence
of anxiety in the study population was 80.5% including 79.3% medicos and 81.9%
non-medicos whereas the prevalence of depression was 73.3% including 74.7%
medicos and 71.7% non-medicos. There are paucities of studies from India
exploring the prevalence of anxiety and depression during the COVID-19 pandemic
making any comparison difficult, but the high
prevalence of anxiety and depression in our study emphasizes the urgent need
for strengthening the preventive, therapeutic and curative mental health care
services in India. Depression and anxiety
are the most common psychiatric disorders with a prevalence of 10% to 20% in
the general population.[12] In China, one of the first studies during
COVID-19 among essential workers documented 20.1% prevalence of anxiety
accessed by Beck Anxiety Inventory (BAI) and
12.7% prevalence of depressive symptoms accessed by Beck Depression
Inventory-II (BDI-II) [16], which is very low as compared to our study. Another study
conducted in China showed moderate to severe anxiety symptoms in 28.8% and
moderate to severe depressive symptoms in 16.5% of the respondents accessed by the
Depression, Anxiety and Stress Scale (DASS-21).[17]
Among
the general population, the prevalence of anxiety for found to be in the range
of 2 to 37% in China, 7.2 to 11.5% in Italy, 1.2 to 4% in
Spain and about 28% in India Whereas the prevalence of depression was
reported to be in the range of 8.3 to 48.3% in China, 15.4 to 17% in Italy,
1.7% to 8.7% in Spain and about 25% in India accessed by using different tools
for estimation of anxiety and depression, whereas we used GAD-7 and PHQ-9
scales.[13]
A meta-analysis found 23.2% pooled prevalence of
anxiety and 22.8% depression accessed by different scales including GAD-7 and
PHQ-9 scales.[18] Another systematic review
and meta-analysis involving 31
studies from South Asian countries reported 41.3% pooled prevalence of anxiety
during COVID-19 accessed using different assessment scales. Similarly, 28
studies using different assessment scales reported 34.1% pooled prevalence of
depression during COVID-19. GAD-7 and PHQ-9 were the most frequently used
assessment scales.[19] Differences in the estimated overall prevalence of mental
health disorders in various studies are thought to be because of different
methodologies, population size, heterogeneity in study
population and differences in diagnostic or screening criteria used.[20] GAD-7 accessed
higher prevalence of anxiety (49.2%) compared to DASS-21 (34.2%) and HADS
(32.8%) scales. Similarly, PHQ-9 accessed higher prevalence (34.7%) of
depression as compared to DASS-21 (29.8%) and HADS (29.2%) [19] So the use of GAD-7 and PHQ-9
in our study may be the reason for very high prevalence of anxiety and
depression. Studies from India and Singapore documented 15.7% and 10.6%
prevalence of anxiety and depression among HCWs [21] and 64.7% reported from Turkey both
studies using the DASS-21 scale.[22] Similarly, the study by Kazmi et al. [23] documented the highest prevalence of
anxiety and depression of 57% and 61.1% respectively using the DASS-21 scale.
Prevalence of anxiety and depression in a web survey from Brazil and Spain was
shown to be 8.3% and 11.6% for depression and anxiety respectively using GAD-7
and PHQ-9 scales.[20] A cross-sectional study conducted
in 359 South Indian medical students showed that 75.5% had anxiety symptoms
accessed by GAD-7 scale and 74.6% had depression symptoms accessed by CES-D
scale which were comparable to the
results of our study. Another cross-sectional survey showed that
25.1% of the subjects were depressed and 28% were anxious over the last 3 weeks
accessed by DASS-21 scale.[24]
A meta-analysis documented 43.6%
pooled prevalence of anxiety among HCWs and 40.7% among the general population,
whereas the pooled prevalence of depression was (39%) higher in the general
population than (29.9%) among HCWs.[19] This also is less as compared to our
study. Another meta-analysis showed 73%
prevalence of anxiety among Egyptian medical students, 50.1% prevalence of
anxiety among Hong Kong nurses, 10.5% prevalence
of anxiety in the general American population, 20.9% prevalence of depression
among physicians which is less as compared to the prevalence of anxiety and
depression among medicos group in our survey.[12] In our study, the prevalence
of anxiety according to severity scales in medicos was 20.7% had no anxiety,
40.2% mild anxiety, 30.7% moderate and 8.3% severe anxiety whereas in the
non-medicos group 18.1% had no anxiety, 44.0% mild anxiety, 32.5% moderate and
5.4% severe anxiety. The results of our study were somewhat high as compared to
the study showing 34% mild anxiety, 20% moderate anxiety and 14.8% moderately
severe anxiety and 6.7% showed symptoms of severe anxiety using GAD-7 scales.[5] Data analysis in our
survey shows that in the medicos group, 25.3% had no depression, 39.8% had
minimal depression, 27.6% mild depression, 5.8% moderate depression, 1.3%
moderately severe depression and 0.0% suffered from severe depression whereas,
among non-medicos group, 28.3% had no depression, 37.7% minimal depression,
28.6% mild depression, 4.7% moderate depression, 0.7% moderately severe
depression and 0.0% had severe depression. The results of our study were high
as compared to a study showing 30.1% had
mild depression, 20.3% moderate depression, 15.3% moderately severe depression
and 8.9% had severe depression symptoms using CES-D scales.[25] In
our survey, according to gender, the prevalence of anxiety was 78.3% in males,
84.5% in females, including 78.1% in males and 81.6% in females among the
medicos group, 78.4% in males and 87.3% in females among the non-medicos group.
Almost similar prevalence was observed in South Indian medical students’
study where 73.5% males and 77.5% females
showed the presence of anxiety symptoms using GAD-7 scales.[25] In our study
prevalence of anxiety according to the level of severity was 43.9% mild
anxiety, 27.8% moderate anxiety and 6.5% severe anxiety in males and 32.7% mild
anxiety, 36.8% moderate anxiety and 12% severe anxiety in females among the
medicos group. Among the non-medicos group, it was 55.5% mild anxiety, 19.7%
moderate anxiety and 3.3% severe anxiety in males and 27.7% mild anxiety, 50.9%
moderate anxiety and 8.4% severe anxiety in females. Prevalence of anxiety
according to the level of severity in South Indian medical students'
study was observed to be mild anxiety 38.7%
males and 29.2% females, moderate anxiety in 17.7% males and 22.5%
females, moderately severe anxiety in
11.6% males and 17.9% females and severe anxiety was observed in 5.5% males and 7.9% female students using
GAD-7 and CES-D scales.[25] In our survey, the predominance of the
prevalence of anxiety among females than males was observed, which was similar
to the observation by the National mental health survey
of India 2015–2016.[8]
Prevalence of
depression related to gender observed in our study population was 69.7% in
males, 79.3% in females and medicos group, the prevalence of depression was
74.1% in males and 75.9% in females whereas in the non-medicos group it was
64.3% in males and 82.3% in females. Prevalence of depression related to gender
observed in South Indian medical students’ study using CES-D scales [25] was 72.9%
in males and 76.4% in females with females showing more prevalence than males
like in our study. In our study prevalence of depression according to the level
of severity related to gender in medicos was observed to be minimal depression
in 43.5% males, 32.3% females, mild depression in 24.8% males, 33.6% females,
moderate depression in 5.0% males, 7.5% females, moderately severe depression
in 0.8% males, 2.5% females and severe depression was observed in 0.1% males
and 0.0% in females. Similarly in the non-medicos group minimal depression was
observed in 42.0% males, 31.4% females, mild depression in 19.1% males, 42.1%
females, moderate depression in 2.8% males, 7.6% females, moderately severe
depression in 0.4% males, 1.2% females and severe depression was observed none
of the males or females. Prevalence of depression according to the level of
severity in South Indian medical students’ study [25] related
to gender showed that 72.9% males and 76.4%
females had depression, including mild depression in 31.5% males, 28.6%
females, moderate depression in 18.8% males, 21.9% females, moderately severe
depression in 15.4% males, 15.2% females and severe depression was observed in
7.2% males and 10.7% females. The similar predominance of females over males
had been documented by the National mental health survey
of India 2015–2016.[8]
There are paucities of studies comparing the prevalence of anxiety and depression based on region and our study observed 82.0% prevalence of anxiety in the Punjab group, 78.8% outside the Punjab group and the difference was statistically significant (0.008). The difference in the prevalence of anxiety in medicos and non-medicos according to the region was statistically not significant. Similarly, the prevalence of depression was observed to be 72.8.0% in the Punjab group and 73.8% outside the Punjab group and the difference was statistically not significant (0.431), whereas the difference of prevalence of depression in medicos and non-medicos according to the region was statistically significant (0.018) in Punjab group and statistically not significant (0.703) outside Punjab groups.
Data analysis show that 57.9% of the total study population, 63.7% medico and 51.7% non-medicos did not have any difficulty at all to do work, whereas somewhat difficulty was felt by 38.3 % of the total study population, 32.4% medico and 44.6% non-medicos, many difficulties were experienced by 3.0 % of the total study population, 3.0% medico and 3.1% non-medicos and the extremely difficult situation was experienced by 0.8% of the total study population, 0.8% medico and 0.8% non-medicos. The difference observed was statistically highly significant (x2= 68.724; df= 3; p<0.001). Data about the need for treatment by the study population showed that 69.9% of the total study population, 66.7% medicos and 73.5% non-medicos did not take any treatment for anxiety or depression, whereas 27.2% of the total study population, 30.5% medicos and 23.6% of non-medicos took occasional treatment and only 2.9% of the total study population, 2.9%medicos and 2.9% non-medicos took treatment regularly. The difference between medicos and non-medicos was observed to be statistically highly significant. (x2= 25.750; df= 2; p < 0.001)
Results of our study, necessitate initiation of measures to curb, decrease and minimize the increasing prevalence of mental health disorders and psychiatric morbidity during Covid-19 pandemic like psychological interventions, supports for high-risk population, education for identification of mental health issues, awareness of psychiatric symptoms, curbing media exposure, break from work, increased peer support and easy access to psychiatric help through different methods of social media and telemedicine will help in reducing the psychological and psychiatric morbidity.[26] In India mental health scenario in the pre-COVID-19 era was grim with psychiatric issues becoming more complicated during the COVID-19 pandemic because of the high prevalence of pre-existing mental disorders, deficient mental health care infrastructure and help, huge deprived population, uncontrolled information and misinformation on social, electronic and print media.[27] Keeping in mind, India specific COVID and mental health conditions, Government of India (GOI)-MOHFW issued Psycho-Social toll-free helpline-08046110007 and web portal providing access to stress coping strategies, advice, videos, meditation and yoga practices to help people especially the vulnerable section of society to take care of their mental health issues.
Very
high prevalence of anxiety and depression documented by our study also justify
the NIMHANS suggestion to form a 'Psychological intervention medical team’
competent to formulate mental health interventions strategies to address mental
health issues during the COVID-19 pandemic.[28] Results of our survey suggest initiation of urgent measures to address
mental health issues and their psychological impacts to contain and curb grave
adverse effects of mental disorders including anxiety and depression.
CONCLUSIONS-
Results
of our survey suggest a high prevalence of anxiety and depression in the Indian
population. More people were found to be suffering from mild anxiety and mild
depression during the COVID-19 pandemic. Socio-demographic variables like age
groups, gender, region and job status influenced the
prevalence of anxiety and depression in the study population as well as among
medico and non-medico groups. Results of our survey may be helpful for the
policymakers and the government to initiate and device diagnostic, preventive
and management strategies to address the psychological
as well as psychiatric needs of the Indian population. Because, the
Mental Healthcare Act, 2017 guaranteed the right to mental health care for the
Indian population, the findings of this survey will help identify mental health
care needs during these challenging times of the COVID-19 pandemic to initiate
appropriate measures to promote the mental well-being of our population with
initiating infrastructure strengthening and recruiting sufficient mental health
care professionals.
CONTRIBUTION OF AUTHORS
Research concept- Meghna Gupta, Vitull K Gupta, Navjot Kaur
Research
design- Meghna Gupta, Vitull K Gupta, Navjot
Kaur
Supervision- Meghna Gupta, Vitull K
Gupta, Navjot Kaur
Materials- Meghna Gupta, Vitull K Gupta, Navjot Kaur, Parneet
K. Hari, Kashish Goyal
Data
collection- Meghna Gupta, Vitull K Gupta, Navjot Kaur, Parneet K. Hari, Kashish Goyal
Data
analysis and Interpretation- Meghna Gupta, Vitull K Gupta, Navjot Kaur, Parneet K. Hari, Kashish Goyal
Literature
search- Meghna Gupta, Vitull K Gupta, Navjot Kaur, Parneet K. Hari, Kashish Goyal
Writing
article- Meghna Gupta, Vitull K Gupta, Navjot Kaur, Parneet K. Hari, Kashish Goyal
Critical
review- Meghna Gupta, Vitull K Gupta, Navjot Kaur
Article
editing- Meghna Gupta, Vitull K Gupta, Navjot Kaur, Parneet K. Hari, Kashish Goyal
Final approval- Meghna Gupta, Vitull
K Gupta, Navjot Kaur, Parneet K. Hari, Kashish Goyal
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